Protection from
infection. CUVITRU [Immune Globulin Subcutaneous
(Human)] 20% is a primary immunodeficiency
treatment that offers consistent Ig levels in between
infusions, protection from infection, * and a flexible
treatment schedule.¹ ,²
Your healthcare team will teach you how to administer
CUVITRU, step by step, so you can infuse at home.¹
* The goal of the clinical study was to look at the rate of acute
serious bacterial infections (ASBIs) in patients receiving
treatment. Patients on CUVITRU experienced 0.012 ASBIs per
patient per year, which is significantly less than the FDA’s
standard of 1 ASBI per patient per year for determining if the
treatment works. Only one ASBI occurred in CUVITRU’s clinical
study; it was a case of pneumonia in a 78-year-old patient.

Your doctor is your best resource for questions. Learn more at CUVITRU.com.

What is CUVITRU?
CUVITRU is a ready-to-use liquid
medicine that is given under the skin
(subcutaneously) to treat primary
immunodeficiency (PI) in people
2 years and older.

IMPORTANT SAFETY
INFORMATION What is the most important
information I need to know
about CUVITRU?
CUVITRU can cause the
following serious reactions:
• Severe allergic reactions
causing difficulty in breathing
or skin rashes
• Decreased kidney function or
kidney failure
• Blood clots in the heart, brain,
lungs, or elsewhere in the body
• Severe headache, drowsiness,
fever, painful eye movements,
or nausea and vomiting
• Dark colored urine, swelling,
fatigue, or difficulty breathing
Who should not use CUVITRU?
Do not use CUVITRU if you:
• Have had a severe allergic
reaction to immune globulin
or other blood products.

• Have a condition called selective
(or severe) immunoglobulin A
(IgA) deficiency.

What should I avoid while
taking CUVITRU?
• CUVITRU can make vaccines
(like measles/mumps/rubella or
chickenpox vaccines) not work
as well for you. Before you get
any vaccines, tell your healthcare
provider (HCP) that you take
CUVITRU. • Tell your HCP if you are pregnant,
or plan to become pregnant, or if
you are nursing.

What are the possible or
reasonably likely side effects
of CUVITRU?
CUVITRU can cause serious side
effects. If any of the following
problems occur after starting
CUVITRU, stop the infusion
immediately and contact your
HCP or call emergency services.

©2021 Takeda Pharmaceuticals U.S.A., Inc. 300 Shire Way, Lexington, MA 02421. 1-877-TAKEDA-7 (1-877-825-3327). All rights reserved. TAKEDA and the TAKEDA logo are trademarks or
registered trademarks of Takeda Pharmaceutical Company Limited. CUVITRU and the CUVITRU logo are trademarks or registered trademarks of Baxalta Incorporated, a Takeda company.

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